BrainMax SAMe, 400 mg, 60 vegetable capsules
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BrainMax SAMe, 400 mg, 60 vegetable capsules
BrainMax SAMe, 400 mg
Conductor of whole body biochemistry
Few substances in the human body are involved in as many reactions as SAMe. This inconspicuous molecule, formed by the union of methionine and ATP energy, is at the heart of cellular biochemistry. Thanks to its ability to transfer methyl groups, it influences hundreds of processes ranging from gene regulation to the formation of cell building blocks. It is important in methylation, the formation of glutathione or the neurotransmitters dopamine and serotonin.
Universal molecule
Creation of ATP
The power of biochemistry
From neurotransmitters to membranes
SAMe is closely linked to the production of neurotransmitters. Due to its role in methylation, it is involved in the synthesis of dopamine, serotonin and norepinephrine. Equally important is its action on cell membranes, where it helps the conversion of phospholipids and thus maintains the correct structure and flexibility of neuronal cells.
Where SAMe plays a major role
The majority of SAMe is formed in the liver, from where it is involved in many key metabolic pathways. It is a precursor of polyamines, such as spermidine, which are small molecules closely associated with regeneration. In addition, very important substances are formed from homocysteine, which is produced during the metabolism of SAMe:
- Glutathione
- Cysteine
- Taurine
With what other products to combine?
- B-complex - involved in the methionine and homocysteine cycle, where SAMe plays a key role
- NAC- binds to SAMe metabolic pathways and participates in glutathione synthesis
- Inositol - often combined with substances associated with the formation of neurotansmitters
- Magnesium - a mineral involved in hundreds of enzymatic reactions
- Omega-3 - a combination to support cell membranes
Nutritional values and composition
| Nutritional component | Quantity in 1 dose |
|---|---|
| S-adenosyl-L-methionine | 400 mg |
S-adenosyl-L-methionine (400 mg, RHP**), stabilizer and anti-caking agent: microcrystalline cellulose and silica. HPMC-based plant capsule. May contain traces of egg, soy and milk. Silica gel is included.
Dosage
1 capsule per day.
Package size:
60 vegetable capsules, 47.3 g.
Storage
Store at room temperature, in a dry and dark place. Do not remove the silica gel from the jar and make sure the cap is always securely closed.
Notice
Keep out of reach of children! The product is not intended for use by children, pregnant or nursing women unless recommended by a physician. Do not exceed the recommended daily dosage. The product is not intended as a substitute for a varied diet. Maintain a healthy lifestyle.
Verified by studies
Bottiglieri, T. (2002). S-Adenosyl-L-methionine (SAMe): From the bench to the bedside-Molecular basis of a pleiotrophic molecule. The American Journal of Clinical Nutrition, 76(5), 1151S-1157S.
Delle Chiaie, R., Pancheri, P., & Scapicchio, P. (2002). Efficacy and tolerability of oral and intramuscular S-adenosyl-L-methionine in the treatment of major depression: A meta-analysis of randomized controlled trials. The American Journal of Medicine, 113(6), 476-485.
Mischoulon, D., & Fava, M. (2014). Role of S-adenosyl-L-methionine in the treatment of depression: A review of the evidence. The American Journal of Clinical Nutrition, 100(suppl_1), 445S-449S.
Cuomo, A., Beccarini Crescenzi, B., Bolognesi, S., Goracci, Proietti, L., & Bolognesi, E. (2020). The efficacy and safety of S-adenosyl-L-methionine in major depressive disorder: A systematic review and meta-analysis of randomized clinical trials. Annals of General Psychiatry, 19, 8.
Anstee, Q. M., & Day, C. P. (2012). S-adenosylmethionine (SAMe) therapy in liver disease: A review of current evidence and clinical utility. Journal of Hepatology, 57(5), 1097-1109.
Hire, W. I., Reinsch, S., Hoehler, F., Tobis, J. S., & Harvey, P. W. (2004). S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: A double-blind cross-over trial. BMC Musculoskeletal Disorders, 5, 6.
Specifications
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BRAINMARKET s.r.o., Hladnovská. 83/93, Ostrava 702 00, Czech Republic, [email protected]
Specifications can be changed without notice. Images are for illustrative purposes only.
